PROTECTIVE EFFECT OF ÖKÜZGÖZÜ (VITIS VINIFERA L. CV.) SEED EXTRACT AGAINST HYDROXYL RADICAL INDUCED DNA DAMAGE

Published in Scientific Papers. Series B, Horticulture, Volume LXI
Written by Mihdiye PİRİNÇÇİOĞLU, Göksel KIZIL, Bircan ÇEKEN TOPTANCI, Gültekin ÖZDEMIR, Murat KIZIL

Grape is one of the most commonly consumed fruits in the world. It has various biological functions, due to its potential of rich polyphenol ingredients, most of which are contained in its seeds (70%) and skin (30%).The aim of this study was to investigate the protective role of Öküzgözü cv. grape seed extracts against hydroxyl radical that induced oxidative DNA damage. The results revealed that the presence of various concentrations of grape seed extract in the reaction mixture significantly inhibited DNA damage induced by reactive oxygen species (ROS). In conclusion, the results demonstrated that Öküzgözü cv. grape seed extracts protected DNA against hydroxyl radical that induced oxidative damage and the extract could be used as a valuable food supplement or a nutraceutical product.

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PİRİNÇÇİOĞLU M., KIZIL G., ÇEKEN TOPTANCI B., ÖZDEMIR G., KIZIL M. 2017, PROTECTIVE EFFECT OF ÖKÜZGÖZÜ (VITIS VINIFERA L. CV.) SEED EXTRACT AGAINST HYDROXYL RADICAL INDUCED DNA DAMAGE. Scientific Papers. Series B, Horticulture, Volume LXI, Print ISSN 2285-5653, 205-208.


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